Publications

The CHILDS Trust Medical Research Foundation (CTMRF) publication from 2020 to 2025 (6 years)

The Clinical Translational Microbiome Research Foundation (CTMRF) has contributed significantly to pediatric infectious disease research, antimicrobial resistance, immunology, and public health. The research team has published extensively in leading national and international peer-reviewed journals including The Lancet, Nature Medicine, PLOS Pathogens, JAMA Network Open, BMJ Open, and The New England Journal of Medicine.

The publications focus on a wide range of critical healthcare topics such as:

Multisystem Inflammatory Syndrome in Children (MIS-C) and COVID-19 related complications

Pediatric infectious diseases and respiratory infections

Antimicrobial resistance and enteric fever surveillance

Vaccine impact and immunization studies

Clinical microbiology and molecular diagnostics

Pediatric oncology and critical care infections

Epidemiology and public health surveillance

Through collaborative research and multicenter studies across India and internationally, CTMRF continues to advance scientific knowledge and improve clinical outcomes in children. The organization remains committed to evidence-based medicine, innovative diagnostics, and translational research that bridges laboratory discoveries with clinical practice.

The Selected Publications list (year wise or journal wise)

  1. Epidemiological and Clinical Profile of Pediatric Inflammatory Multisystem Syndrome — Temporally Associated with SARS-CoV-2 (PIMS-TS) in Indian Children. INDP 57, 1010–1014 (2020)
  2. Impact of the covid-19 pandemic on admissions to the pediatric emergency department in a tertiary care hospital. Indian j pediatr. 2021 apr;88(4):392. Doi: 10.1007/s12098-020-03562-y. Epub 2020 nov 4.
  3. Hospital based sentinel surveillance for streptococcus pneumoniae and other invasive bacterial diseases in india (hbsspibd): Design and methodology, bmj open 2020.
  4. Postnatal management of bilateral grade 3-4 ureteropelvic junction obstruction. Indian j urol. 2020 oct-dec;36(4):288-294.
  5. Utility of a multiplex real-time polymerase chain reaction for combined detection and serotyping of dengue virus in paediatric patients hospitalised with severe dengue: A report from chennai. Indian j med microbiol. 2020 jul-dec;38(3 & 4):288-292.
  6. Intussusception after rotavirus vaccine introduction in india. N engl j med. 2020 nov 12;383(20):1932-1940.
  7. A survey of humidified high-flow nasal cannula usage in indian pediatric intensive care units. Indian j crit care med. 2020 oct;24(10):996-998.
  8. Public engagement as the fifth dimension of outbreak communication: Public’s perceptions of public health communication during covid-19 in india. Health communication, 38(2), 285–297.
  9. Designing dynamic interventions to improve adherence in pediatric long-term treatment—The role of perceived value of the physician by primary caregivers. Health communication, 36(14), 1825–1840.
  10. Mmr vaccine and covid-19: A myth or a low risk-high reward preventive measure? Indian pediatr. 2020 aug 15;57(8):773.
  11. Rosette-forming glioneuronal tumor in the optic pathway of a child. J pediatr hematol oncol. 2020 oct;42(7):e655-e658.
  12. Coronavirus disease 2019 (covid-19) in children - What we know so far and what we do not. Indian pediatr 57, 435–442 (2020).
  13. Hyperinflammatory syndrome in children associated with covid-19: Need for awareness. Indian pediatr. 2020 oct 15;57(10):929-935.
  14. Hyper-inflammatory syndrome in a child with covid-19 treated successfully with intravenous immunoglobulin and tocilizumab. Indian pediatr. 2020 jul 15;57(7):681-683.
  15. Does a crying child enhance the risk for covid-19 transmission? Indian pediatr. 2020 jun 15;57(6):586-587.
  16. Acrodermatitis enteropathica as a presentation of cystic fibrosis in an infant. Indian pediatr. 2020 jun 15;57(6):573.
  17. Page kidney in a child with severe pelviureteric junction obstruction. Case rep urol. 2020 aug 20;2020:8883546.
  18. Outcomes for high-risk hepatoblastoma in a resource-challenged setting. Bjs open. 2020 aug;4(4):630-636.
  19. Seroprevalence to sars-cov-2 among healthcare workers in an exclusive pediatric hospital. Indian pediatr 2021;58:279-280.
  20. Prolidase deficiency in very early onset inflammatory bowel disease (veo-ibd). Indian j pediatr. 2021 may;88(5):503.
  21. Use of proper personal protective measures among parents of children attending outpatient department — An observational study. Indian j pediatr 88, 480 (2021).
  22. Laboratory diagnosis of covid-19 in secondary care hospitals in india: Will standalone serology suffice? World j pediatr. 2021 feb;17(1):8-9.
  23. Correlation of sars-cov-2 serology and clinical phenotype amongst hospitalised children in a tertiary children's hospital in india. J trop pediatr. 2021 jan 29;67(1):fmab015.
  24. Evaluation of serum procalcitonin, serum interleukin-6, and interleukin-8 as predictors of serious infection in children with febrile neutropenia and cancer. Indian j cancer. 2021 apr-jun;58(2):185-189.
  25. Safety and feasibility of antibiotic de-escalation in critically ill children with sepsis - A prospective analytical study from a pediatric icu. Front pediatr. 2021 mar 8;9:640857.
  26. Preclinical evaluation of sol-gel synthesized modulated 45s5-bioglass based biodegradable bone graft intended for alveolar bone regeneration. Journal of hard tissue biology, 2021, volume 30, issue 3, pages 303-308.
  27. A child with unilateral pulmonary edema due to mitral valve rupture following blunt trauma. Indian j crit care med. 2021 jun;25(6):729-731.
  28. Evaluation of antimicrobial susceptibility profile in salmonella typhi and salmonella paratyphi A:Presenting the current scenario in india and strategy for future management, the journal of infectious diseases, volume 224, issue supplement_5, 15 november 2021, pages s502–s516.
  29. Ileal perforation and enteric fever: Implications for burden of disease estimation, the journal of infectious diseases, volume 224, issue supplement_5, 15 november 2021, pages s522–s528.
  30. Cost of illness due to severe enteric fever in india, the journal of infectious diseases, volume 224, issue supplement_5, 15 november 2021, pages s540–s547.
  31. Systemic inflammation and microbial translocation are characteristic features of sars-cov-2-related multisystem inflammatory syndrome in children. Open forum infectious diseases, volume 8, issue 7, july 2021.
  32. Activity of novel lactone ketolide nafithromycin against multicentric invasive and non-invasive pneumococcal isolates collected in india (accepted for publication in jac-anti microbial resistance: 2021).
  33. Plasma biomarker profiling of pims-ts, covid-19 and sars-cov2 seropositive children – A cross-sectional observational study from southern india. Ebiomedicine, published by the lancet, volume 66, apr 2021;103317.
  34. Evaluation of real time pcr with serology for diagnosis of community acquired pneumonia caused by mycoplasma pneumonia. 2022. Clinical epidemiology and global health, volume 16, july–august 2022, 101084.
  35. A study on pediatric respiratory tract infections in hospitalised children from chennai 2022, clinical epidemiology and global health, volume 15, may–june 2022, 101067.
  36. Role of matrix metalloproteinases in multi-system inflammatory syndrome and acute covid-19 in children. Front. Med. 9:1050804. Doi: 10.3389/fmed.2022.1050804, 05 december 2022.
  37. Unique cellular immune signatures of multisystem inflammatory syndrome in children. Plos pathog 18(11):e1010915. November 2, 2022.
  38. Epidemiology of multidrug resistance among salmonella enterica serovars typhi and paratyphi a at a tertiary pediatric hospital in india over a decade; in-silico approach to elucidate the molecular mechanism of quinolone resistance, international journal of infectious diseases, volume 119, p146-149, june 2022.
  39. Clinical features and risk factors for death in acute undifferentiated fever: A prospective observational study in rural community hospitals in six states of india. Transactions of the royal society of tropical medicine and hygiene, volume 117, issue 2, february 2023, pages 91–101.
  40. Rsv infections: Clinical significance of single versus mixed infections. Biomed rev j basic appl med sci. 2023;10(1):45-47.
  41. Unravelling the nssnp mediated mechanism of antibiotic resistance in salmonella enterica serovar typhi and identification of potential therapeutic alternatives: A genomics and structural bioinformatics study. Clinical epidemiology and global health, volume 24, november–december 2023, 101407.
  42. Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 salmonella typhi genomes. Elife 12:e85867.
  43. Levels of complement components in children with acute covid-19 or multisystem inflammatory syndrome. Jama netw open. 2023;6(3):e231713.
  44. Alterations of adipokines, pancreatic hormones and incretins in acute and convalescent covid-19 children. Bmc pediatr 23, 156 (2023).
  45. Evaluation of real time pcr detection of the 47 kda gene for reliable diagnosis of pediatric scrun typhus. Zoonoses. 2024 vol. 4(1).
  46. Designing a conserved immunogenic peptide construct from the nucleocapsid protein of puumala orthohantavirus. Viruses 2024 jun 26;16(7):1030.
  47. Antimicrobial susceptibility of methicillin-resistant staphylococcus aureus and methicillin-sensitive staphylococcus aureus in a pediatric tertiary care hospital in southern india. Ann child health. August 2024;1:21-4.
  48. Whole genome analysis reveals unique traits of sars-cov-2 in pediatric patients. Gene. Volume 919, 15 august 2024, 148508.
  49. Clinical profile of febrile neutropenia in children with malignancies in a tertiary care hospital: A prospective observational study. Indian journal of medical and paediatric oncology. August 2024;46(01):077-086.
  50. Gbd 2021 antimicrobial resistance collaborators (ctmrf was a collaborator): Global burden of bacterial antimicrobial resistance 1990-2021: A systematic analysis with forecasts to 2050. Lancet. Sep 2024;404(10459):1199-1226. Doi: 10.1016/s0140-6736(24)01867-1.
  51. Frequency and clinical outcomes of respiratory infections in children with cancer presenting with febrile illness. South asian journal of cancer. Oct 2024. Doi: 10.1055/s-0044-1791970.
  52. Sex-specific differences in systemic immune responses in mis-c children. Sci rep 14, 1720 (2024). Https://doi.org/10.1038/s41598-024-52116-1.
  53. The awareness, attitudes and knowledge of pediatricians in tamil nadu india of sudden unexpected death in epilepsy (sudep) and epilepsy related risks: A cross-sectional study. Jan 2025. Epilepsy & behavior, volume 164, 110286.
  54. Nasotragal length or tochen for endotracheal tip trial. J pediatric adv res. Feb 2025;4(1):1-8.
  55. Outcome of injection sclerotherapy with doxycycline in lymphatic, and veno-lymphatic malformation in children: A single centre experience. March 2025, journal of pediatric surgery, volume 60, issue 3, 162054.
  56. Association between dengue and pediatric auf: A study from chennai and kochi, south india. Clinical epidemiology and global health, volume 34, july–august 2025, 102063.
  57. Ceftriaxone and azithromycin minimum inhibitory concentration of salmonella typhi and paratyphi a blood isolates of children with enteric fever. Ann child health. Doi: 10.25259/ach_2_2025.
  58. Impact of the indigenous rotavirus vaccine rotavac in the universal immunization program in india during 2016–2020. Nat med 31, 3871–3878 (2025).
  59. Scarlet fever - A retrospective case series in the midst of recent upsurge of cases in india. Indian j med microbiol. 2026 jan-feb;59:101040. Doi: 10.1016/j.ijmmb.2025.101040. Epub 2025 dec 15.
  60. Extra-intestinal salmonellosis presenting as infected ovarian teratoma in an adolescent with prolonged fever. Indian pediatr 63, 139–140.